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2015). Methcathinone derivatives with equal affinity for DAT and SERT or better affinity for SERT above DAT show empathogenic Houses. They induce moderate enhance of locomotor activity and therefore are endowed with a lessen abuse likely compared with pyrovalerones (Bonano et al. 2015; Eshleman et al. 2017).together with in cases by which 3-CMC was